Do you prefer to create products or work with already defined products?

The more definition you expect when you start working with a product or company, the less likely you would be to enjoy a start-up, or at least one in the early idea stages.

What happens if the company redefines itself? What if the product evolves, or the company's business model evolves?

The more averse you are to changing conditions, either in the product or a the way the company operates, the more comfortable you will be working in an established company rather than a start-up.

Do you prefer to define your role within a company or have your position well-determined?

The more entrepreneurial you are, the more likely you are to enjoy the flexibility inherent in start-up positions.

What are the average number of hours per week you find yourself working in a full-time position?

If you gravitate toward 40 to 45 hours per week, you might fit better in a larger company -- a 90-hour week might be what a start-up requires.

How many management team positions do you want to see filled before you start? How many people should be at the company?

The more you expect from the company at the point in which you enter the picture, the more mature or developed the company you target should be.

Would you work for a reduced salary or for a couple of months without a paycheck? What pure financial risk would you consider?

Assess your complete financial situation. If you are willing to undertake some financial burden for potential payoffs down the road, you are better suited for a fledgling start-up. The more financial stability you need, the older and more developed the company should be.